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The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family.... more
Product information "Anti-PTPRE"
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Several alternatively spliced transcript variants of this gene have been reported, at least two of which encode a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokine-induced SATA signaling, as well as the activation of voltage-gated K+ channels. Protein function: Isoform 1 plays a critical role in signaling transduction pathways and phosphoprotein network topology in red blood cells. May play a role in osteoclast formation and function. [The UniProt Consortium]
Keywords: | Anti-PTPRE, EC=3.1.3.48, Anti-R-PTP-epsilon, Anti-Protein-tyrosine phosphatase epsilon, Anti-Receptor-type tyrosine-protein phosphatase epsilon, PTPRE Polyclonal Antibody |
Supplier: | Elabscience |
Supplier-Nr: | E-AB-61586 |
Properties
Application: | WB, IHC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | Recombinant protein of human PTPRE |
Database Information
KEGG ID : | K18033 | Matching products |
UniProt ID : | P23469 | Matching products |
Gene ID | GeneID 5791 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | 4°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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