Anti-PTPN1, ID (PTPN1, PTP1B, Tyrosine-protein phosphatase non-receptor type 1, Protein-tyrosine pho

Anti-PTPN1, ID (PTPN1, PTP1B, Tyrosine-protein phosphatase non-receptor type 1, Protein-tyrosine pho
Item number Size Datasheet Manual SDS Delivery time Quantity Price
040658.200 200 µl - -

1 - 19 business days

557.00€
 
The protein encoded by this gene is the founding member of the protein tyrosine phosphatase (PTP)... more
Product information "Anti-PTPN1, ID (PTPN1, PTP1B, Tyrosine-protein phosphatase non-receptor type 1, Protein-tyrosine pho"
The protein encoded by this gene is the founding member of the protein tyrosine phosphatase (PTP) family, which was isolated and identified based on its enzymatic activity and amino acid sequence. PTPs catalyze the hydrolysis of the phosphate monoesters specifically on tyrosine residues. Members of the PTP family share a highly conserved catalytic motif, which is essential for the catalytic activity. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP has been shown to act as a negative regulator of insulin signaling by dephosphorylating the phosphotryosine residues of insulin receptor kinase. This PTP was also reported to dephosphorylate epidermal growth factor receptor kinase, as well as JAK2 and TYK2 kinases, which implicated the role of this PTP in cell growth control, and cell response to interferon stimulation. Applications: Suitable for use in Western Blot, ELISA, Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-500, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-PTP1B, Anti-PTPN1, Anti-PTP-1B, EC=3.1.3.48, Anti-Protein-tyrosine phosphatase 1B, Anti-Tyrosine-protein phosphatase non-receptor type 1
Supplier: United States Biological
Supplier-Nr: 040658

Properties

Application: ELISA, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Mouse
Immunogen: PTPN1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 221-249 amino acids from the Central region of human PTPN1.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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