Anti-PSME1, CT (PSME1, IFI5111, Proteasome activator complex subunit 1, 11S regulator complex subuni

Anti-PSME1, CT (PSME1, IFI5111, Proteasome activator complex subunit 1, 11S regulator complex subuni
Item number Size Datasheet Manual SDS Delivery time Quantity Price
040571.200 200 µl - -

1 - 19 business days

557.00€
 
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure... more
Product information "Anti-PSME1, CT (PSME1, IFI5111, Proteasome activator complex subunit 1, 11S regulator complex subuni"
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. The immunoproteasome contains an alternate regulator, referred to as the 11S regulator or PA28, that replaces the 19S regulator. Three subunits (alpha, beta and gamma) of the 11S regulator have been identified. This gene encodes the alpha subunit of the 11S regulator, one of the two 11S subunits that is induced by gamma-interferon. Three alpha and three beta subunits combine to form a heterohexameric ring. Applications: Suitable for use in Western Blot, Immunohistochemistry, Flow Cytometry, ELISA, Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-500, Immunohistochemistry: 1:50-100, Flow Cytometry: 1:10-50, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-PSME1, Anti-PA28a, Anti-IFI5111, Anti-PA28alpha, Anti-REG-alpha, Anti-IGUP I-5111, Anti-11S regulator complex subunit alpha, Anti-Proteasome activator 28 subunit alpha, Anti-Proteasome activator complex subunit 1
Supplier: United States Biological
Supplier-Nr: 040571

Properties

Application: ELISA, FC, IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human
Immunogen: PSME1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 219-258 amino acids from the C-terminal region of human PSME1.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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