Anti-PSMD14

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A303-857A-T	10 µl (10 µg)		-		2 - 8 business days*		164.00€
A303-857A	100 µl (100 µg)		-		2 - 8 business days*		588.00€

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Protein function: Metalloprotease component of the 26S proteasome that specifically cleaves... more

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Product information "Anti-PSMD14"

Protein function: Metalloprotease component of the 26S proteasome that specifically cleaves 'Lys-63'-linked polyubiquitin chains. The 26S proteasome is involved in the ATP-dependent degradation of ubiquitinated proteins. Plays a role in response to double-strand breaks (DSBs): acts as a regulator of non-homologous end joining (NHEJ) by cleaving 'Lys-63'-linked polyubiquitin, thereby promoting retention of JMJD2A/KDM4A on chromatin and restricting TP53BP1 accumulation. Also involved in homologous recombination repair by promoting RAD51 loading. [The UniProt Consortium]

Keywords:	Anti-POH1, Anti-PSMD14, EC=3.4.19.-, Anti-26S proteasome regulatory subunit RPN11, Anti-26S proteasome-associated PAD1 homolog 1, Anti-26S proteasome non-ATPase regulatory subunit 14
Supplier:	Bethyl Laboratories
Supplier-Nr:	A303-857A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse (Expected: rat, zebrafish, X. laevis, X. tropicalis, chicken, turkey, bovine, horse, guinea pig_10141, pig, panda, orangutan, rhesus monkey, gorilla, chimpanzee, west indian ocean coelacanth, channel catfish, atlantic salmon, sablefish)
Immunogen:	synthetic peptide. The epitope recognized by A303-857A-T maps to a region between residue 260 and 310 of human Proteasome (Prosome, Macropain) 26S Subunit, non-ATPase, 14 using the numbering given in entry NP_005796.1 (GeneID 10213).
Format:	Antigen Affinity Purified