Anti-PSMC6

Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AB-60935.60 60 µl -

7 - 16 business days*

198.00€
E-AB-60935.120 120 µl -

7 - 16 business days*

317.00€
E-AB-60935.200 200 µl -

7 - 16 business days*

525.00€
 
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure... more
Product information "Anti-PSMC6"
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. Pseudogenes have been identified on chromosomes 8 and 12. Protein function: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC6 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides. [The UniProt Consortium]
Keywords: Anti-SUG2, Anti-PSMC6, Anti-Proteasome subunit p42, Anti-Proteasome 26S subunit ATPase 6, Anti-26S proteasome regulatory subunit 10B, Anti-26S proteasome AAA-ATPase subunit RPT4, PSMC6 Polyclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AB-60935

Properties

Application: WB, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Recombinant protein of human PSMC6

Handling & Safety

Storage: -20°C
Shipping: 4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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