Anti-PSMB10

Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AB-61800.60 60 µl -

7 - 16 business days*

198.00€
E-AB-61800.120 120 µl -

7 - 16 business days*

317.00€
E-AB-61800.200 200 µl -

7 - 16 business days*

525.00€
 
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core... more
Product information "Anti-PSMB10"
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Proteolytic processing is required to generate a mature subunit. Expression of this gene is induced by gamma interferon, and this gene product replaces catalytic subunit 2 (proteasome beta 7 subunit) in the immunoproteasome. Protein function: The proteasome is a multicatalytic proteinase complex which is characterized by its ability to cleave peptides with Arg, Phe, Tyr, Leu, and Glu adjacent to the leaving group at neutral or slightly basic pH. The proteasome has an ATP-dependent proteolytic activity. This subunit is involved in antigen processing to generate class I binding peptides. [The UniProt Consortium]
Keywords: Anti-LMP10, Anti-PSMB10, EC=3.4.25.1, Anti-Proteasome MECl-1, Anti-Macropain subunit MECl-1, Anti-Proteasome subunit beta-2i, Anti-Low molecular mass protein 10, Anti-Proteasome subunit beta type-10, PSMB10 Polyclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AB-61800

Properties

Application: WB, IHC, IF
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Recombinant protein of human PSMB10

Handling & Safety

Storage: -20°C
Shipping: 4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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