Anti-Protein Kinase A, RegII beta, (PKA RIIb)

Anti-Protein Kinase A, RegII beta, (PKA RIIb)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
P9102-91L2.40 40 µg - -

3 - 19 business days*

346.00€
 
The cAMP-dependent protein kinase (PKA) is a critical kinase involved in numerous biological... more
Product information "Anti-Protein Kinase A, RegII beta, (PKA RIIb)"
The cAMP-dependent protein kinase (PKA) is a critical kinase involved in numerous biological functions. The PKA holoenzyme is composed of two regulatory and two catalytic subunits, designated PKA R and PKA C, respectively. PKA regulatory (PKA R) subunits exist as two classes, RI and RII, with each class containing two isoforms, alpha and beta. Three catalytic subunit isoforms, Calpha, Cbeta, and Cgamma, have been identified. The PKA R subunits allow a range of modifying agents to influence PKA activity and localization, and are found in different levels in a tissue-specific manner. Upon PKA R subunit binding to the second messenger cAMP, active PKA C subunits are released, initiating a phosphorylation cascade that regulates such cellular functions as metabolism, ion transport, and gene transcription. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 0.05-0.2ug/ml, Western Blot: 0.5-2ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Supplier: United States Biological
Supplier-Nr: P9102-91L2

Properties

Application: ELISA, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Mouse
Immunogen: Synthetic peptide (KLH). derived from human PKA regulatory II subunit (PKA RII )
Purity: Purified by immunoaffinity chromatography.
Format: Affinity Purified

Database Information

Handling & Safety

Storage: -20°C (-20°C Glycerol)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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