Anti-Prostaglandin D Synthase (hematopoietic-type, human) (Clone 2A5)

Anti-Prostaglandin D Synthase (hematopoietic-type, human) (Clone 2A5)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
Cay10004345-1 1 each -

3 - 10 business days*

324.00€
 
Prostaglandin D synthase (PGDS) catalyzes the isomerization of PGH2 to produce PGD2. PGD2 induces... more
Product information "Anti-Prostaglandin D Synthase (hematopoietic-type, human) (Clone 2A5)"
Prostaglandin D synthase (PGDS) catalyzes the isomerization of PGH2 to produce PGD2. PGD2 induces sleep, regulates nociception, inhibits platelet aggregation and acts as an allergic mediator. Two distinct types of PGDS have been identified, namely the lipocalin-type enzyme (beta-trace) and the hematopoietic enzyme. Lipocalin-type PGDS is localized in the central nervous system and male genital organs of various mammals and the human heart. This enzyme has been identified as beta-trace, which is a major protein in human cerebrospinal fluid. Hematopoietic PGDS is widely distributed in the peripheral tissues and is localized in the antigen-presenting cells, mast cells, and megakaryocytes. This enzyme, which requires glutathione for activity, belongs to the sigma-class of Glutathione-S-Transferases and is approximately 23 kDa in size. Cayman Chemical's H-PGDS Monoclonal Antibody can be used for western blot and immunohistochemical analysis for H-PGDS on samples of human and murine origin. Other applications for use of this antibody have not yet been tested. Synonyms: H-PGD Synthase, H-PGDS. Immunogen: Recombinant human H-PGDS. Clone Designation: 2A5. Formulation: 100 µg Purified IgG. Storage Buffer: PBS, pH 7.2, containing 50% glycerol, 0.5 mg/ml BSA, and 0.02% sodium azide. Host: Mouse. Isotype: IgG2bkappa. Applications: IHC and WB. Origin: Animal/Mouse.
Keywords: H-PGD Synthase, H-PGDS
Supplier: Cayman Chemical
Supplier-Nr: 10004345

Properties

Application: IHC, WB
Antibody Type: Monoclonal
Clone: 2A5
Conjugate: No
Host: Mouse
Reactivity: Human, Mouse
Immunogen: Recombinant human H-PGDS
Format: Purified

Database Information

KEGG ID : K04097 | Find alternatives
UniProt ID : O60760 | Find alternatives

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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