Anti-Prion Protein - SAF 83

Anti-Prion Protein - SAF 83
Item number Size Datasheet Manual SDS Delivery time Quantity Price
BR-A03207.200 200 µg -

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468.00€
 
Protein function: Its primary physiological function is unclear. May play a role in neuronal... more
Product information "Anti-Prion Protein - SAF 83"
Protein function: Its primary physiological function is unclear. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May promote myelin homeostasis through acting as an agonist for ADGRG6 receptor. May play a role in iron uptake and iron homeostasis. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro). Association with GPC1 (via its heparan sulfate chains) targets PRNP to lipid rafts. Also provides Cu(2+) or ZN(2+) for the ascorbate-mediated GPC1 deaminase degradation of its heparan sulfate side chains. [The UniProt Consortium]
Keywords: Anti-PrP, Anti-PRP, Anti-PRNP, Anti-CD230, Anti-PrP27-30, Anti-PrP33-35C, Anti-Major prion protein
Supplier: Bertin Bioreagent
Supplier-Nr: A03207

Properties

Application: WB
Antibody Type: Monoclonal
Clone: SAF 83
Conjugate: No
Host: Mouse
Species reactivity: hamster, mouse, bovine (weak), ovine (weak), human (weak).
Immunogen: preparation of SAF (scrapie associated fibrils) from infected hamster brain.
Format: Lyophilized

Database Information

UniProt ID : P04273 | Matching products
Gene ID GeneID 101829062 | Matching products

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: °C)
GHS Hazard Pictograms:
H Phrases: H300, H373, H400, H410, H412
P Phrases: P273, P501
Caution
Our products are for laboratory research use only: Not for administration to humans!
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