Anti-PPP4C, ID (PPP4C, PPP4, PPX, Serine/threonine-protein phosphatase 4 catalytic subunit, Protein

Anti-PPP4C, ID (PPP4C, PPP4, PPX, Serine/threonine-protein phosphatase 4 catalytic subunit, Protein
Item number Size Datasheet Manual SDS Delivery time Quantity Price
040362.200 200 µl - -

1 - 19 business days

557.00€
 
Protein phosphatase that is involved in many processes such as microtubule organization at... more
Product information "Anti-PPP4C, ID (PPP4C, PPP4, PPX, Serine/threonine-protein phosphatase 4 catalytic subunit, Protein"
Protein phosphatase that is involved in many processes such as microtubule organization at centrosomes, maturation of spliceosomal snRNPs, apoptosis, tumor necrosis factor (TNF)-alpha signaling, activation of c-Jun N-terminal kinase MAPK8, regulation of histone acetylation, DNA damage checkpoint signaling, NF-kappa-B activation and cell migration. The PPP4C-PPP4R1 PP4 complex may play a role in dephosphorylation and regulation of HDAC3. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on Ser-140 (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair. Dephosphorylates NDEL1 at CDK1 phosphorylation sites and negatively regulates CDK1 activity in interphase (By similarity). Applications: Suitable for use in Western Blot, Immunohistochemistry, ELISA, Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-500, Immunohistochemistry: 1:10-50, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-Pp4, Anti-PPP4, Anti-PP4C, Anti-PP-X, Anti-PPP4C, EC=3.1.3.16, Anti-Protein phosphatase X, Anti-Serine/threonine-protein phosphatase 4 catalytic subunit
Supplier: United States Biological
Supplier-Nr: 040362

Properties

Application: ELISA, IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human
Immunogen: PPP4C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 159-189 amino acids from the Central region of human PPP4C.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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