Anti-PPP3CA

Anti-PPP3CA
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*1 Offer expires 31/07/2021
Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AB-60163.60 60 µl - -

7 - 16 business days*

117.00€
E-AB-60163.120 120 µl - -

7 - 16 business days*

208.00€
E-AB-60163.200 200 µl - -

7 - 16 business days*

363.00€
 
Protein function: Calcium-dependent, calmodulin-stimulated protein phosphatase which plays an... more
Product information "Anti-PPP3CA"
Protein function: Calcium-dependent, calmodulin-stimulated protein phosphatase which plays an essential role in the transduction of intracellular Ca(2+)-mediated signals (PubMed:15671020, PubMed:18838687, PubMed:19154138, PubMed:23468591). Many of the substrates contain a PxIxIT motif and/or a LxVP motif (PubMed:17498738, PubMed:17502104, PubMed:23468591, PubMed:27974827, PubMed:22343722). In response to increased Ca(2+) levels, dephosphorylates and activates phosphatase SSH1 which results in cofilin dephosphorylation (PubMed:15671020). In response to increased Ca(2+) levels following mitochondrial depolarization, dephosphorylates DNM1L inducing DNM1L translocation to the mitochondrion (PubMed:18838687). Dephosphorylates heat shock protein HSPB1. Dephosphorylates and activates transcription factor NFATC1 (PubMed:19154138). In response to increased Ca(2+) levels, regulates NFAT-mediated transcription probably by dephosphorylating NFAT and promoting its nuclear translocation (PubMed:26248042). Dephosphorylates and inactivates transcription factor ELK1 (PubMed:19154138). Dephosphorylates DARPP32 (PubMed:19154138). [The UniProt Consortium]
Keywords: Anti-CALNA, Anti-CAM-PRP catalytic subunit, Anti-Calmodulin-dependent calcineurin A subunit alpha isoform, Anti-Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform, PPP3CA Polyclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AB-60163

Properties

Application: WB, IF
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein of human PPP3CA

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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