Anti-PPM1F, ID (PPM1F, KIAA0015, POPX2, Protein phosphatase 1F, Ca(2+)/calmodulin-dependent protein

Anti-PPM1F, ID (PPM1F, KIAA0015, POPX2, Protein phosphatase 1F, Ca(2+)/calmodulin-dependent protein
Item number Size Datasheet Manual SDS Delivery time Quantity Price
040325.200 200 µl - -

1 - 19 business days

557.00€
 
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases.... more
Product information "Anti-PPM1F, ID (PPM1F, KIAA0015, POPX2, Protein phosphatase 1F, Ca(2+)/calmodulin-dependent protein"
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase can interact with Rho guanine nucleotide exchange factors (PIX), and thus block the effects of p21-activated kinase 1 (PAK), a protein kinase mediating biological effects downstream of Rho GTPases. Calcium/calmodulin-dependent protein kinase II gamma (CAMK2G/CAMK-II) is found to be one of the substrates of this phosphatase. The overexpression of this phosphatase or CAMK2G has been shown to mediate caspase-dependent apoptosis. An alternatively spliced transcript variant has been identified, but its full-length nature has not been determined. Applications: Suitable for use in Western Blot and ELISA. Other applications not tested. Recommended Dilutions: Western Blot: 1:1000, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-PPM1F, Anti-hFem-2, Anti-CaMKPase, Anti-KIAA0015, EC=3.1.3.16, Anti-Partner of PIX 2, Anti-Protein fem-2 homolog, Anti-CaM-kinase phosphatase, Anti-Protein phosphatase 1F, Anti-Ca(2+)/calmodulin-dependent protein kinase phosphatase
Supplier: United States Biological
Supplier-Nr: 040325

Properties

Application: ELISA, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human
Immunogen: PPM1F antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 275-303 amino acids from the Central region of human PPM1F.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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