Anti-PPM1A (PPM1A, PPPM1A, Protein phosphatase 1A, Protein phosphatase 2C isoform alpha, Protein pho

Anti-PPM1A (PPM1A, PPPM1A, Protein phosphatase 1A, Protein phosphatase 2C isoform alpha, Protein pho
Item number Size Datasheet Manual SDS Delivery time Quantity Price
040323.200 200 µl - -

1 - 19 business days

557.00€
 
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases.... more
Product information "Anti-PPM1A (PPM1A, PPPM1A, Protein phosphatase 1A, Protein phosphatase 2C isoform alpha, Protein pho"
The protein encoded by this gene is a member of the PP2C family of Ser/Thr protein phosphatases. PP2C family members are known to be negative regulators of cell stress response pathways. This phosphatase dephosphorylates, and negatively regulates the activities of, MAP kinases and MAP kinase kinases. It has been shown to inhibit the activation of p38 and JNK kinase cascades induced by environmental stresses. This phosphatase can also dephosphorylate cyclin-dependent kinases, and thus may be involved in cell cycle control. Overexpression of this phosphatase is reported to activate the expression of the tumor suppressor gene TP53/p53, which leads to G2/M cell cycle arrest and apoptosis. Three alternatively spliced transcript variants encoding distinct isoforms have been described. Applications: Suitable for use in Western Blot, ELISA, Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-500, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-PPM1A, Anti-PPPM1A, Anti-PP2C-alpha, EC=3.1.3.16, Anti-Protein phosphatase IA, Anti-Protein phosphatase 1A, Anti-Protein phosphatase 2C isoform alpha
Supplier: United States Biological
Supplier-Nr: 040323

Properties

Application: ELISA, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human
Immunogen: PPM1A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from human PPM1A.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-PPM1A (PPM1A, PPPM1A, Protein phosphatase 1A, Protein phosphatase 2C isoform alpha, Protein pho"
Write a review
or to review a product.
Viewed