Anti-POLR3C, ID (POLR3C, DNA-directed RNA polymerase III subunit RPC3, DNA-directed RNA polymerase I

Anti-POLR3C, ID (POLR3C, DNA-directed RNA polymerase III subunit RPC3, DNA-directed RNA polymerase I
Item number Size Datasheet Manual SDS Delivery time Quantity Price
040266.200 200 µl - -

1 - 19 business days

557.00€
 
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four... more
Product information "Anti-POLR3C, ID (POLR3C, DNA-directed RNA polymerase III subunit RPC3, DNA-directed RNA polymerase I"
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Specific core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. May direct with other members of the subcomplex RNA Pol III binding to the TFIIIB-DNA complex via the interactions between TFIIIB and POLR3F. May be involved either in the recruitment and stabilization of the subcomplex within RNA polymerase III, or in stimulating catalytic functions of other subunits during initiation. Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF-Kappa-B through the RIG-I pathway. Applications: Suitable for use in Western Blot, ELISA, Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-500, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-RPC62, Anti-POLR3C, Anti-RNA polymerase III subunit C3, Anti-RNA polymerase III 62 kDa subunit, Anti-DNA-directed RNA polymerase III subunit C, Anti-DNA-directed RNA polymerase III subunit RPC3
Supplier: United States Biological
Supplier-Nr: 040266

Properties

Application: ELISA, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human
Immunogen: POLR3C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 201-230 amino acids from the Central region of human POLR3C.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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