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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
040265-FITC.200 | 200 µl | - | - |
3 - 19 business days* |
993.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four... more
Product information "Anti-POLR3B, NT (POLR3B, DNA-directed RNA polymerase III subunit RPC2, C128, DNA-directed RNA polyme"
DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Second largest core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Proposed to contribute to the polymerase catalytic activity and forms the polymerase active center together with the largest subunit. Pol III is composed of mobile elements and RPC2 is part of the core element with the central large cleft and probably a clamp element that moves to open and close the cleft (By similarity). Plays a key role in sensing and limiting infection by intracellular bacteria and DNA viruses. Acts as nuclear and cytosolic DNA sensor involved in innate immune response. Can sense non-self dsDNA that serves as template for transcription into dsRNA. The non-self RNA polymerase III transcripts, such as Epstein-Barr virus-encoded RNAs (EBERs) induce type I interferon and NF-Kappa-B through the RIG-I pathway. Applications: Suitable for use in Western Blot, FLISA, Recommended Dilution: FLISA: 1:1,000, Western Blot: 1:100-500, Storage and Stability: Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. , , Note: Applications are based on unconjugated antibody.
Keywords: | Anti-C128, Anti-POLR3B, EC=2.7.7.6, Anti-RNA polymerase III subunit C2, Anti-DNA-directed RNA polymerase III subunit B, Anti-DNA-directed RNA polymerase III subunit RPC2, Anti-DNA-directed RNA polymerase III 127.6 kDa polypeptide |
Supplier: | United States Biological |
Supplier-Nr: | 040265-FITC |
Properties
Application: | FLISA, WB |
Antibody Type: | Polyclonal |
Conjugate: | FITC |
Host: | Rabbit |
Species reactivity: | mouse |
Immunogen: | POLR3B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 329-359 amino acids from the N-terminal region of human POLR3B. |
Format: | Affinity Purified |
Database Information
KEGG ID : | K03021 | Matching products |
UniProt ID : | Q9NW08 | Matching products |
Gene ID | GeneID 55703 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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