Anti-PNN/Pinin

Anti-PNN/Pinin
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A301-022A-T 10 µl (10 µg) -

2 - 8 business days*

164.00€
A301-022A 100 µl (100 µg) -

2 - 8 business days*

588.00€
 
Protein function: Transcriptional activator binding to the E-box 1 core sequence of the... more
Product information "Anti-PNN/Pinin"
Protein function: Transcriptional activator binding to the E-box 1 core sequence of the E-cadherin promoter gene, the core-binding sequence is 5'CAGGTG-3'. Capable of reversing CTBP1-mediated transcription repression. Auxiliary component of the splicing- dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Participates in the regulation of alternative pre-mRNA splicing. Associates to spliced mRNA within 60 nt upstream of the 5'-splice sites. Component of the PSAP complex which binds RNA in a sequence-independent manner and is proposed to be recruited to the EJC prior to or during the splicing process and to regulate specific excision of introns in specific transcription subsets. Involved in the establishment and maintenance of epithelia cell- cell adhesion. Potential tumor suppressor for renal cell carcinoma. [The UniProt Consortium]
Keywords: Anti-DRS, Anti-PNN, Anti-DRSP, Anti-Pinin, Anti-DRS protein, Anti-SR-like protein, Anti-Nuclear protein SDK3, Anti-Domain-rich serine protein, Anti-Desmosome-associated protein, Anti-Melanoma metastasis clone A protein
Supplier: Bethyl Laboratories
Supplier-Nr: A301-022A

Properties

Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse (Expected: dog, orangutan)
Immunogen: synthetic peptide. The epitope recognized by A301-022A-T maps to a region between residue 667 and the C-terminus (residue 717) of human Pinin, desmosome associated protein using the numbering given in entry NP_002678.2 (GeneID 5411).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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