Anti-PLK3, CT (PLK3, CNK, FNK, PRK, Serine/threonine-protein kinase PLK3, Cytokine-inducible serine/

Anti-PLK3, CT (PLK3, CNK, FNK, PRK, Serine/threonine-protein kinase PLK3, Cytokine-inducible serine/
Item number Size Datasheet Manual SDS Delivery time Quantity Price
040174.200 200 µl - -

1 - 19 business days

557.00€
 
CNK, a member of the CDC5/Polo subfamily of Ser/Thr protein kinases, is involved in regulating M... more
Product information "Anti-PLK3, CT (PLK3, CNK, FNK, PRK, Serine/threonine-protein kinase PLK3, Cytokine-inducible serine/"
CNK, a member of the CDC5/Polo subfamily of Ser/Thr protein kinases, is involved in regulating M phase functions during the cell cycle. It may also be part of the signaling network controlling cellular adhesion. In vitro, is able to phosphorylate CDC25C and casein. This membrane-associated protein binds to the calcium/integrin-binding protein (CIB). This interaction probably occurs via the POLO-box domain. Transcripts are highly detected in placenta, lung, followed by skeletal muscle, heart, pancreas, ovaries and kidney and weakly detected in liver and brain. This protein exhibits a short half-live. In cells of hematopoietic origin, CNK is strongly and exclusively detected in terminally differentiated macrophages. Transcript expression appears to be down-regulated in primary lung tumor. Cytokine and cellular adhesion trigger CNK induction. CNK is thought to be phosphorylated as cells enter mitosis and dephosphorylated as cells exit mitosis The protein contains 2 POLO box domains. Applications: Suitable for use in Western Blot, ELISA, Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-500, Flow cytometry, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-CNK, Anti-PLK3, Anti-PLK-3, EC=2.7.11.21, Anti-Polo-like kinase 3, Anti-FGF-inducible kinase, Anti-Proliferation-related kinase, Anti-Serine/threonine-protein kinase PLK3, Anti-Cytokine-inducible serine/threonine-protein kinase
Supplier: United States Biological
Supplier-Nr: 040174

Properties

Application: ELISA, FC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Mouse
Immunogen: PLK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 617~646 amino acids from the C-terminal region of human PLK3.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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