Anti-Plakoglobin

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A303-717A-T	10 µl (10 µg)		-		2 - 8 business days*		164.00€
A303-717A	100 µl (100 µg)		-		2 - 8 business days*		588.00€

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Protein function: Common junctional plaque protein. The membrane- associated plaques are... more

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Product information "Anti-Plakoglobin"

Protein function: Common junctional plaque protein. The membrane- associated plaques are architectural elements in an important strategic position to influence the arrangement and function of both the cytoskeleton and the cells within the tissue. The presence of plakoglobin in both the desmosomes and in the intermediate junctions suggests that it plays a central role in the structure and function of submembranous plaques. Acts as a substrate for VE-PTP and is required by it to stimulate VE- cadherin function in endothelial cells. Can replace beta-catenin in E-cadherin/catenin adhesion complexes which are proposed to couple cadherins to the actin cytoskeleton. [The UniProt Consortium]

Keywords:	Anti-JUP, Anti-CTNNG, Anti-Catenin gamma, Anti-Desmoplakin-3, Anti-Desmoplakin III, Anti-Junction plakoglobin
Supplier:	Bethyl Laboratories
Supplier-Nr:	A303-717A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: rabbit, rhesus monkey, gorilla, chimpanzee, crab-eating macaque, northern white-cheeked gibbon)
Immunogen:	synthetic peptide. The epitope recognized by A303-717A-T maps to a region between residue 1 and 50 of human Junction Plakoglobin using the numbering given in entry NP_002221.1 (GeneID 3728).
Format:	Antigen Affinity Purified