Anti-PKC beta2, CT (PRKCB, PKCB, PRKCB1, Protein kinase C beta type)

Anti-PKC beta2, CT (PRKCB, PKCB, PRKCB1, Protein kinase C beta type)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
040091.200 200 µl - -

1 - 19 business days

557.00€
 
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be... more
Product information "Anti-PKC beta2, CT (PRKCB, PKCB, PRKCB1, Protein kinase C beta type)"
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role in cells. PKC beta is one of the PKC family members. This protein kinase has been reported to be involved in many different cellular functions, such as B cell activation, apoptosis induction, endothelial cell proliferation, and intestinal sugar absorption. Studies in mice also suggest that this kinase may also regulate neuronal functions and correlate fear-induced conflict behavior after stress. Alternatively spliced transcript variants encoding distinct isoforms have been reported. Isoform 1 uses an alternate exon at the 3' end compared to isoform 2, which includes a part of the coding region. The resulting isoform 1 has a distinct and shorter C-terminus, as compared to isoform 2. Applications: Suitable for use in Western Blot, ELISA, Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-500, Immunohistochemistry: 1:10-50, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-PKCB, Anti-PKC-B, Anti-PRKCB, Anti-PKC-beta, EC=2.7.11.13, Anti-Protein kinase C beta type
Supplier: United States Biological
Supplier-Nr: 040091

Properties

Application: ELISA, IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Monkey, Mouse, Rat
Immunogen: PKC beta2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 644~673 amino acids from the C-terminal region of human PKC beta2.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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