Anti-Pim1, CT (Pim1, Pim-1, Serine/threonine-protein kinase pim-1)

Anti-Pim1, CT (Pim1, Pim-1, Serine/threonine-protein kinase pim-1)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
040059.200 200 µl - -

1 - 19 business days

557.00€
 
Pim1 may affect the structure or silencing of chromatin by phosphorylating HP1 gamma/CBX3 (By... more
Product information "Anti-Pim1, CT (Pim1, Pim-1, Serine/threonine-protein kinase pim-1)"
Pim1 may affect the structure or silencing of chromatin by phosphorylating HP1 gamma/CBX3 (By similarity). Promotes the G1/S transition of the cell cycle via up-regulation of CDK2 activity and phosphorylation of CDKN1B, resulting in enhanced nuclear export and proteasome-dependent degradation of CDKN1B (By similarity). Also represses CDKN1B transcription by phosphorylating and inactivating the transcription factor FOXO3 (By similarity). Plays a role in signal transduction in blood cells (By similarity). Contributes to both cell proliferation and survival thus providing a selective advantage in tumorigenesis (By similarity). Applications: Suitable for use in Western Blot, ELISA, Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-500, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-Pim1, Anti-Pim-1, EC=2.7.11.1, Anti-Serine/threonine-protein kinase pim-1
Supplier: United States Biological
Supplier-Nr: 040059

Properties

Application: ELISA, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Mouse
Immunogen: Mouse Pim1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 342-372 amino acids from the C-terminal region of Mouse Pim1.
Format: Affinity Purified

Database Information

KEGG ID : K04702 | Find alternatives
UniProt ID : P06803 | Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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