Anti-PIF1

Anti-PIF1
Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG45943.50 50 µg - -

6 - 14 business days*

518.00€
 
Protein function: DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of... more
Product information "Anti-PIF1"
Protein function: DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. Efficiently unwinds G-quadruplex (G4) DNA structures and forked RNA-DNA hybrids. Resolves G4 structures, preventing replication pausing and double-strand breaks (DSBs) at G4 motifs. Involved in the maintenance of telomeric DNA. Inhibits telomere elongation, de novo telomere formation and telomere addition to DSBs via catalytic inhibition of telomerase. Reduces the processivity of telomerase by displacing active telomerase from DNA ends. Releases telomerase by unwinding the short telomerase RNA/telomeric DNA hybrid that is the intermediate in the telomerase reaction. Possesses an intrinsic strand annealing activity. [The UniProt Consortium]
Keywords: Anti-C15orf20, Anti-ATP-dependent DNA helicase PIF1, Anti-ATP-dependent DNA helicase PIF1, Anti-PIF1/RRM3 DNA helicase-like protein, Anti-PIF1/RRM3 DNA helicase-like protein, Anti-DNA repair and recombination helicase PIF1, Anti-DNA repair and recombinati
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG45943

Properties

Application: FC, IHC (paraffin), WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Recombinant protein containing to human PIF1
MW: 77 kD
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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