Anti-PHF2

Anti-PHF2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
A303-457A-T 20 µl (2 blots) -

3 - 9 business days*

131.00€
A303-457A-M 100 µl (10 blots) -

3 - 9 business days*

313.00€
A303-457A 100 µl (100 µg) -

3 - 9 business days*

465.00€
 
Protein function: Lysine demethylase that demethylates both histones and non-histone proteins.... more
Product information "Anti-PHF2"
Protein function: Lysine demethylase that demethylates both histones and non-histone proteins. Enzymatically inactive by itself, and becomes active following phosphorylation by PKA: forms a complex with ARID5B and mediates demethylation of methylated ARID5B. Demethylation of ARID5B leads to target the PHF2-ARID5B complex to target promoters, where PHF2 mediates demethylation of dimethylated 'Lys-9' of histone H3 (H3K9me2), followed by transcription activation of target genes. The PHF2-ARID5B complex acts as a coactivator of HNF4A in liver. PHF2 is recruited to trimethylated 'Lys-4' of histone H3 (H3K4me3) at rDNA promoters and promotes expression of rDNA. [The UniProt Consortium]
Keywords: Anti-GRC5, EC=1.14.11.-, Anti-PHD finger protein 2, Anti-Lysine-specific demethylase PHF2
Supplier: Bethyl Laboratories
Supplier-Nr: A303-457A

Properties

Application: WB, IP
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human (Expected: Orangutan, Rhesus Monkey, Gorilla, Chimpanzee, White-tufted-ear Marmoset, Crab-eating Macaque, Small-eared Galago)
Immunogen: synthetic peptide. The epitope recognized by A303-457A-T maps to a region between residue 650 and 700 of human PHD finger protein 2 using the numbering given in entry NP_005383.3 (GeneID 5253).
Format: Antigen Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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