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| Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
|---|---|---|---|---|---|---|---|
| A303-457A-T | 10 µl (10 µg) | - |
2 - 8 business days* |
164.00€
|
|||
| A303-457A | 100 µl (100 µg) | - |
2 - 8 business days* |
588.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Protein function: Lysine demethylase that demethylates both histones and non-histone proteins.... more
Product information "Anti-PHF2"
Protein function: Lysine demethylase that demethylates both histones and non-histone proteins. Enzymatically inactive by itself, and becomes active following phosphorylation by PKA: forms a complex with ARID5B and mediates demethylation of methylated ARID5B. Demethylation of ARID5B leads to target the PHF2-ARID5B complex to target promoters, where PHF2 mediates demethylation of dimethylated 'Lys-9' of histone H3 (H3K9me2), followed by transcription activation of target genes. The PHF2-ARID5B complex acts as a coactivator of HNF4A in liver. PHF2 is recruited to trimethylated 'Lys-4' of histone H3 (H3K4me3) at rDNA promoters and promotes expression of rDNA. [The UniProt Consortium]
| Keywords: | Anti-GRC5, EC=1.14.11.-, Anti-PHD finger protein 2, Anti-Lysine-specific demethylase PHF2 |
| Supplier: | Bethyl Laboratories |
| Supplier-Nr: | A303-457A |
Properties
| Application: | WB, IP |
| Antibody Type: | Polyclonal |
| Conjugate: | No |
| Host: | Rabbit |
| Species reactivity: | human (Expected: orangutan, rhesus monkey, gorilla, chimpanzee, white-tufted-ear marmoset, crab-eating macaque, small-eared galago) |
| Immunogen: | synthetic peptide. The epitope recognized by A303-457A-T maps to a region between residue 650 and 700 of human PHD finger protein 2 using the numbering given in entry NP_005383.3 (GeneID 5253). |
| Format: | Antigen Affinity Purified |
Database Information
| KEGG ID : | K19414 | Matching products |
| UniProt ID : | O75151 | Matching products |
| Gene ID | GeneID 5253 | Matching products |
Handling & Safety
| Storage: | +4°C |
| Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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