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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
ARG57423.100 | 100 µl | - | - |
6 - 14 business days* |
624.00€
|
Protein function: Polycomb group (PcG) that specifically binds histone H3 trimethylated at... more
Product information "Anti-PHF19"
Protein function: Polycomb group (PcG) that specifically binds histone H3 trimethylated at 'Lys-36' (H3K36me3) and recruits the PRC2 complex. Probably involved in the transition from an active state to a repressed state in embryonic stem cells: acts by binding to H3K36me3, a mark for transcriptional activation, and recruiting H3K36me3 histone demethylases RIOX1 or KDM2B, leading to demethylation of H3K36 and recruitment of the PRC2 complex that mediates H3K27me3 methylation, followed by de novo silencing. Recruits the PRC2 complex to CpG islands and contributes to embryonic stem cell self-renewal. Also binds dimethylated at 'Lys- 36' (H3K36me2). Isoform 1 and isoform 2 inhibit transcription from an HSV-tk promoter. [The UniProt Consortium]
Keywords: | Anti-PCL3, Anti-hPCL3, Anti-PHF19, Anti-PHD finger protein 19, Anti-Polycomb-like protein 3 |
Supplier: | Arigo Biolaboratories |
Supplier-Nr: | ARG57423 |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | mouse, rat (Expected: human) |
Immunogen: | Recombinant protein of Human PHF19 |
MW: | 66 kD |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K11486 | Matching products |
UniProt ID : | Q5T6S3 | Matching products |
Gene ID | GeneID 26147 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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