Anti-Periplakin, CT (PPL, Paraneoplastic Pemphigus Antigen, 195kD Cornified Envelope Precursor, AW55

Anti-Periplakin, CT (PPL, Paraneoplastic Pemphigus Antigen, 195kD Cornified Envelope Precursor, AW55
Item number Size Datasheet Manual SDS Delivery time Quantity Price
040322.200 200 µl - -

1 - 19 business days

557.00€
 
The protein encoded by this gene is a component of desmosomes and of the epidermal cornified... more
Product information "Anti-Periplakin, CT (PPL, Paraneoplastic Pemphigus Antigen, 195kD Cornified Envelope Precursor, AW55"
The protein encoded by this gene is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling. [provided by RefSeq]. Applications: Suitable for use in Western Blot, Immunohistochemistry, ELISA, Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-500, Immunohistochemistry: 1:10-50, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-PPL, Anti-KIAA0568, Anti-Periplakin, Anti-190 kDa paraneoplastic pemphigus antigen, Anti-195 kDa cornified envelope precursor protein
Supplier: United States Biological
Supplier-Nr: 040322

Properties

Application: ELISA, IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human
Immunogen: PPL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1300-1331 amino acids from the C-terminal region of human PPL.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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