Anti-PDZD3, ID (PDZD3, IKEPP, NHERF4, PDZK2, Na(+)/H(+) exchange regulatory cofactor NHE-RF4, Intest

Anti-PDZD3, ID (PDZD3, IKEPP, NHERF4, PDZK2, Na(+)/H(+) exchange regulatory cofactor NHE-RF4, Intest
Item number Size Datasheet Manual SDS Delivery time Quantity Price
039861.200 200 µl - -

1 - 19 business days

557.00€
 
Guanylyl cyclase C (GCC, or GUCY2C, MIM 601330) produces cGMP following the binding of either... more
Product information "Anti-PDZD3, ID (PDZD3, IKEPP, NHERF4, PDZK2, Na(+)/H(+) exchange regulatory cofactor NHE-RF4, Intest"
Guanylyl cyclase C (GCC, or GUCY2C, MIM 601330) produces cGMP following the binding of either endogenous ligands or heat-stable enterotoxins secreted by E. coli and other enteric bacteria. Activation of GCC initiates a signaling cascade that leads to phosphorylation of the cystic fibrosis transmembrane conductance regulator (CFTR, MIM 602421), followed by a net efflux of ions and water into the intestinal lumen. IKEPP is a regulatory protein that associates with GCC and regulates the amount of cGMP produced following receptor stimulation (Scott et al., 2002 [PubMed 11950846]). Applications: Suitable for use in Western Blot, ELISA, Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-500, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-PDZD3, Anti-IKEPP, Anti-DLNB27, Anti-NHERF-4, Anti-NaPi-Cap2, Anti-PDZ domain-containing protein 2, Anti-PDZ domain-containing protein 3, Anti-Intestinal and kidney-enriched PDZ protein, Anti-Sodium-hydrogen exchanger regulatory factor 4
Supplier: United States Biological
Supplier-Nr: 039861

Properties

Application: ELISA, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human
Immunogen: PDZD3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 257-285 amino acids from the Central region of human PDZD3.
Format: Affinity Purified

Database Information

UniProt ID : Q86UT5 | Find alternatives
Gene ID GeneID 79849 | Find alternatives

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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