Anti-PDP1, ID (PDP1, PDP, PPM2C, [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitoc

Anti-PDP1, ID (PDP1, PDP, PPM2C, [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitoc
Item number Size Datasheet Manual SDS Delivery time Quantity Price
039853.200 200 µl - -

1 - 19 business days

557.00€
 
Pyruvate dehydrogenase (E1) is one of the three components (E1, E2, and E3) of the large pyruvate... more
Product information "Anti-PDP1, ID (PDP1, PDP, PPM2C, [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitoc"
Pyruvate dehydrogenase (E1) is one of the three components (E1, E2, and E3) of the large pyruvate dehydrogenase complex. Pyruvate dehydrogenase kinases catalyze phosphorylation of serine residues of E1 to inactivate the E1 component and inhibit the complex. Pyruvate dehydrogenase phosphatases catalyze the dephosphorylation and activation of the E1 component to reverse the effects of pyruvate dehydrogenase kinases. Pyruvate dehydrogenase phosphatase is a heterodimer consisting of catalytic and regulatory subunits. Two catalytic subunits have been reported, one is predominantly expressed in skeletal muscle and another one is is much more abundant in the liver. The catalytic subunit, encoded by this gene, is the former, and belongs to the protein phosphatase 2C (PP2C) superfamily. Along with the pyruvate dehydrogenase complex and pyruvate dehydrogenase kinases, this enzyme is located in the mitochondrial matrix. Mutation in this gene causes pyruvate dehydrogenase phosphatase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. Applications: Suitable for use in Western Blot, Immunohistochemistry, ELISA, Recommended Dilution: ELISA: 1:1,000, Western Blot: 1:100-500, Immunohistochemistry: 1:10-50, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-PDP, Anti-PDP1, Anti-PDP 1, Anti-PDPC 1, EC=3.1.3.43, Anti-Protein phosphatase 2C, Anti-Pyruvate dehydrogenase phosphatase catalytic subunit 1, Anti-[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial
Supplier: United States Biological
Supplier-Nr: 039853

Properties

Application: ELISA, IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human
Immunogen: PDP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 366-395 amino acids from the Central region of human PDP1.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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