Anti-PDP1

Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AB-61893.60 60 µl -

7 - 16 business days*

198.00€
E-AB-61893.120 120 µl -

7 - 16 business days*

317.00€
E-AB-61893.200 200 µl -

7 - 16 business days*

525.00€
 
Pyruvate dehydrogenase (E1) is one of the three components (E1, E2, and E3) of the large pyruvate... more
Product information "Anti-PDP1"
Pyruvate dehydrogenase (E1) is one of the three components (E1, E2, and E3) of the large pyruvate dehydrogenase complex. Pyruvate dehydrogenase kinases catalyze phosphorylation of serine residues of E1 to inactivate the E1 component and inhibit the complex. Pyruvate dehydrogenase phosphatases catalyze the dephosphorylation and activation of the E1 component to reverse the effects of pyruvate dehydrogenase kinases. Pyruvate dehydrogenase phosphatase is a heterodimer consisting of catalytic and regulatory subunits. Two catalytic subunits have been reported, one is predominantly expressed in skeletal muscle and another one is is much more abundant in the liver. The catalytic subunit, encoded by this gene, is the former, and belongs to the protein phosphatase 2C (PP2C) superfamily. Along with the pyruvate dehydrogenase complex and pyruvate dehydrogenase kinases, this enzyme is located in the mitochondrial matrix. Mutation in this gene causes pyruvate dehydrogenase phosphatase deficiency. Multiple alternatively s Protein function: Catalyzes the dephosphorylation and concomitant reactivation of the alpha subunit of the E1 component of the pyruvate dehydrogenase complex. [The UniProt Consortium]
Keywords: Anti-PDP, Anti-PDP1, Anti-PDP 1, Anti-PDPC 1, EC=3.1.3.43, Anti-Protein phosphatase 2C, Anti-Pyruvate dehydrogenase phosphatase catalytic subunit 1, Anti-[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial, PDP1 Polyclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AB-61893

Properties

Application: WB, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: Recombinant protein of human PDP1

Handling & Safety

Storage: -20°C
Shipping: 4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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