Anti-Par4

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
A302-092A-T	10 µl (10 µg)		-		2 - 8 business days*		164.00€
A302-092A	100 µl (100 µg)		-		2 - 8 business days*		588.00€

If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk

Protein function: Pro-apoptopic protein capable of selectively inducing apoptosis in cancer... more

Close menu

Product information "Anti-Par4"

Protein function: Pro-apoptopic protein capable of selectively inducing apoptosis in cancer cells, sensitizing the cells to diverse apoptotic stimuli and causing regression of tumors in animal models. Induces apoptosis in certain cancer cells by activation of the Fas prodeath pathway and coparallel inhibition of NF-kappa-B transcriptional activity. Inhibits the transcriptional activation and augments the transcriptional repression mediated by WT1. Down- regulates the anti-apoptotic protein BCL2 via its interaction with WT1. Seems also to be a transcriptional repressor by itself. May be directly involved in regulating the amyloid precursor protein (APP) cleavage activity of BACE1. [The UniProt Consortium]

Keywords:	Anti-PAR4, Anti-PAWR, Anti-Par-4, Anti-PRKC apoptosis WT1 regulator protein, Anti-Prostate apoptosis response 4 protein
Supplier:	Bethyl Laboratories
Supplier-Nr:	A302-092A

Properties

Application:	WB, IP
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human (Expected: mouse, rat)
Immunogen:	synthetic peptide. The epitope recognized by A302-092A-T maps to a region between residue 290 and 340 of human prostate apoptosis response protein 4 (PRKC, apoptosis, WT1, regulator) using the numbering given in entry NP_002574.2 (GeneID 5074).
Format:	Antigen Affinity Purified