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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-R30069 | 100 µg | - | - |
3 - 10 business days* |
755.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
0.5mg/ml with 1% BSA and 0.01% sodium azide if reconstituted with 0.2ml sterile 1XPBS. Cadherins... more
Product information "Anti-pan-Cadherin, clone PC-79"
0.5mg/ml with 1% BSA and 0.01% sodium azide if reconstituted with 0.2ml sterile 1XPBS. Cadherins are calcium-dependent adhesion molecules that mediate cell-cell binding in a homophilic manner. They play an important role in the growth and development of cells via the mechanisms of control of tissue architecture and the maintenance of tissue integrity. Cadherin expression is regulated spatially as well as temporally. Cadherins are thought to play an important role in development and maintenance of tissues through selective cell-cell adhesion activity and may be involved also in the invasion and metastasis of malignant tumors. Cadherin regulates dendritic spine morphogenesis. A cadherin gene cluster is mapped to a region of chromosome 5 subject to frequent allelic loss in carcinoma. Protein function: Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells, cadherins may thus contribute to the sorting of heterogeneous cell types. CDH1 is involved in mechanisms regulating cell-cell adhesions, mobility and proliferation of epithelial cells. Has a potent invasive suppressor role. It is a ligand for integrin alpha-E/beta-7. [The UniProt Consortium]
Keywords: | Anti-CDH1, Anti-CDHE, pan-Cadherin Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | R30069 |
Properties
Application: | WB, IHC (paraffin) |
Antibody Type: | Monoclonal |
Clone: | PC-79 |
Conjugate: | No |
Host: | Mouse |
Species reactivity: | human, mouse, rat, rabbit, chicken, snake |
Immunogen: | Amino acids 1-24 of chicken N-Cadherin were used as the immunogen for this pan-Cadherin antibody. |
Format: | Purified |
Database Information
KEGG ID : | K05689 | Matching products |
UniProt ID : | P12830 | Matching products |
Gene ID | GeneID 999 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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