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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
600-401-H09 | 100 µg | - | - |
6 - 10 business days* |
684.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
Anti-p53DINP1 Antibody was affinity purified from monospecific antiserum by immunoaffinity... more
Product information "Anti-p53DINP1"
Anti-p53DINP1 Antibody was affinity purified from monospecific antiserum by immunoaffinity purification. A BLAST analysis was used to suggest cross-reactivity with p53DINP1 with Human, Mouse and Rat based on 100% homology with the immunizing sequence. Cross-reactivity with PUMA from other sources has not been determined. p53DINP1 antibody detects human p53DINP1. Apoptosis is related to many diseases and development. The p53 tumor-suppressor protein induces apoptosis through transcriptional activation of several genes. A novel p53 inducible gene was identified recently and designated p53DINP1 (for p53-dependent damage-inducible nuclear protein 1) and SIP (for stress induced protein) in human and mouse. A p53DINP1 antisense oligonucleotide inhibits and overexpression of p53DINP1 enhances Ser46 phosphorylation of p53, induction of p53AIP1, and cell death induced by DNA double-strand breaks. p53DINP1 may regulate p53-dependent apoptosis through phosphorylation at Ser46 and induction of p53AIP1. The p53DINP1/SIP gene encodes two proteins of 27 and 18 kDa in human and mouse termed p53DINP1-alpha and p53DINP1-beta or SIP27 and SIP18. p53DINP1/SIP is expressed in many tissues and induced by a variety of stress agents including UV stress, mutagenic stress, heat shock, and oxidative stress. Anti-p53DINP1 antibodies are ideal for investigators involved in Apoptosis and Cancer research.
Keywords: | Anti-SIP, Anti-p53DINP1, Anti-TP53INP1, Anti-P53DINP1, Anti-Stress-induced protein, Anti-Tumor protein p53-inducible nuclear protein 1, Anti-p53-dependent damage-inducible nuclear protein 1 |
Supplier: | Rockland Immunochemicals |
Supplier-Nr: | 600-401-H09 |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Species reactivity: | human, mouse, rat |
Immunogen: | synthetic peptide corresponding to amino acids near the n-terminus of human p53DINP1. |
Format: | Purified |
Database Information
KEGG ID : | K15310 | Matching products |
UniProt ID : | Q96A56 | Matching products |
Gene ID | GeneID 94241 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | -20°C (International: -20°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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