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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
P1001-97B.100 | 100 µg | - | - |
3 - 19 business days* |
962.00€
|
If you have any questions, please use our Contact Form.
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
You can also order by e-mail: info@biomol.com
Larger quantity required? Request bulk
p130Cas (protein 130kD Crk-associated substrate, also BCAR1) is a cytoplasmic member of the CAS... more
Product information "Anti-p130Cas (Cas for Crk-associated substrate, BCAR1, K-associated Substrate, Breast Cancer anti-es"
p130Cas (protein 130kD Crk-associated substrate, also BCAR1) is a cytoplasmic member of the CAS family of proteins. Although its predicted MW is 93kD, it runs anomalously at 105-130kD in SDS-PAGE. It is found in a wide variety of cell types. p130Cas is involved in cell spreading and migration (but not adhesion), and its cleavage into a 31kD fragment promotes anoikis and cell death. Human p130Cas is 870aa in length. It contains one SH3 domain (aa3-65), a Pro-rich region (aa74-87), at least 10 phosphotyrosine (aa128-410) and four phosphoserine (aa134-639) sites, an SH3 binding motif (aa635-643) and a HLH dimerization segment that interacts with CASL. Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1ug/ml, Optimal dilutions to be determined by the researcher. Storage and Stability: Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS, sterile 40-50% glycerol, 0.02% sodium azide, aliquot and store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Keywords: | Anti-p130cas, Anti-CRK-associated substrate, Anti-Cas scaffolding protein family member 1, Anti-Breast cancer anti-estrogen resistance protein 1 |
Supplier: | United States Biological |
Supplier-Nr: | P1001-97B |
Properties
Application: | WB |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Sheep |
Species reactivity: | human, mouse, rat |
Immunogen: | E. coli-derived recombinant human p130Cas (aa66-412). |
Format: | Affinity Purified |
Database Information
KEGG ID : | K05726 | Matching products |
UniProt ID : | P56945 | Matching products |
Gene ID | GeneID 9564 | Matching products |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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