Anti-Opa1 (Optic Atrophy 1, Optic Atrophy 1 Gene Protein, Optic Atrophy Protein 1, Dynamin-like 120k

Anti-Opa1 (Optic Atrophy 1, Optic Atrophy 1 Gene Protein, Optic Atrophy Protein 1, Dynamin-like 120k
Item number Size Datasheet Manual SDS Delivery time Quantity Price
O7004-85.100 100 µl - -

3 - 19 business days*

546.00€
 
This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related... more
Product information "Anti-Opa1 (Optic Atrophy 1, Optic Atrophy 1 Gene Protein, Optic Atrophy Protein 1, Dynamin-like 120k"
This gene product is a nuclear-encoded mitochondrial protein with similarity to dynamin-related GTPases. It is a component of the mitochondrial network. Mutations in this gene have been associated with optic atrophy type 1, which is a dominantly inherited optic neuropathy resulting in progressive loss of visual acuity, leading in many cases to legal blindness. Eight transcript variants encoding different isoforms, resulting from alternative splicing of exon 4 and two novel exons named 4b and 5b, have been reported for this gene. Cellular Localization: Mitochondrion, mitochondrial inner membrane, single-pass membrane protein. Mitochondrion, mitochondrial intermembrane space. , Applications: , Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Supplier: United States Biological
Supplier-Nr: O7004-85

Properties

Application: IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Chicken, Human, Mouse, Rat
Immunogen: A synthetic peptide made to an internal region within residues 500-600 of the human protein. [Swiss-Prot# O60313]. Homology: 100% human, mouse, rat, and chicken
Purity: Purified by immunoaffinity chromatography.
Format: Affinity Purified

Database Information

Handling & Safety

Storage: -20°C (-20°C Glycerol)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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