Anti-NXF1, NT (NXF1, TAP, Nuclear RNA export factor 1, Tip-associated protein, Tip-associating prote

Anti-NXF1, NT (NXF1, TAP, Nuclear RNA export factor 1, Tip-associated protein, Tip-associating prote
Item number Size Datasheet Manual SDS Delivery time Quantity Price
039228-APC.200 200 µl - -

3 - 19 business days*

993.00€
 
This gene is one member of a family of nuclear RNA export factor genes. Common domain features of... more
Product information "Anti-NXF1, NT (NXF1, TAP, Nuclear RNA export factor 1, Tip-associated protein, Tip-associating prote"
This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene shuttles between the nucleus and the cytoplasm and binds in vivo to poly(A)+ RNA. It is the vertebrate homologue of the yeast protein Mex67p. The encoded protein overcomes the mRNA export block caused by the presence of saturating amounts of CTE (constitutive transport element) RNA of type D retroviruses. Alternative splicing results in multiple transcript variants. Applications: Suitable for use in Western Blot, Immunohistochemistry, FLISA, Recommended Dilution: FLISA: 1:1,000, Western Blot: 1:100-500, Immunohistochemistry: 1:10-50, Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap., , Note: Applications are based on unconjugated antibody.
Keywords: Anti-TAP, Anti-NXF1, Anti-Tip-associated protein, Anti-mRNA export factor TAP, Anti-Tip-associating protein, Anti-Nuclear RNA export factor 1
Supplier: United States Biological
Supplier-Nr: 039228-APC

Properties

Application: FLISA, IHC, WB
Antibody Type: Polyclonal
Conjugate: APC
Host: Rabbit
Species reactivity: human
Immunogen: NXF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human NXF1.
Format: Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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