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Protein function: Component of the nuclear pore complex that has a direct role in nuclear protein... more
Product information "Anti-NUP50"
Protein function: Component of the nuclear pore complex that has a direct role in nuclear protein import (PubMed:20016008). Actively displaces NLSs from importin-alpha, and facilitates disassembly of the importin-alpha:beta-cargo complex and importin recycling (PubMed:20016008). Interacts with regulatory proteins of cell cycle progression including CDKN1B. This interaction is required for correct intracellular transport and degradation of CDKN1B. [The UniProt Consortium]
Keywords: | Anti-NUP50, Anti-PRO1146, Anti-NPAP60L, Anti-Nucleoporin Nup50, Anti-50 kDa nucleoporin, Anti-Nuclear pore complex protein Nup50, Anti-Nuclear pore-associated protein 60 kDa-like |
Supplier: | Bethyl Laboratories |
Supplier-Nr: | A301-783A |
Properties
Application: | WB, IP, IHC |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Reactivity: | Human, Mouse (Expected: Bovine, Orangutan, Rhesus Monkey, Gorilla, Chimpanzee, Crab-eating Macaque, Small-eared Galago, Northern White-cheeked Gibbon) |
Immunogen: | synthetic peptide. The epitope recognized by A301-783A-T maps to a region between residue 418 and 468 of human nucleoporin 50kDa using the numbering given in entry NP_009103.2 (GeneID 10762). |
Format: | Antigen Affinity Purified |
Database Information
KEGG ID : | K14295 | Find alternatives |
UniProt ID : | Q9UKX7 | Find alternatives |
Gene ID | GeneID 10762 | Find alternatives |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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