Anti-NUMBL, CT (NUMBL, Numb-like protein, Numb-related protein)

Anti-NUMBL, CT (NUMBL, Numb-like protein, Numb-related protein)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
039212.200 200 µl - -

1 - 19 business days

557.00€
 
NUMBL plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to... more
Product information "Anti-NUMBL, CT (NUMBL, Numb-like protein, Numb-related protein)"
NUMBL plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of embryonic neurogenesis. Also required postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. Negative regulator of NF-kappa-B signaling pathway. The inhibition of NF-kappa-B activation is mediated at least in part, by preventing MAP3K7IP2 to interact with polyubiquitin chains of TRAF6 and RIPK1 and by stimulating the 'Lys-48'-linked polyubiquitination and degradation of TRAF6 in cortical neurons. Applications: Suitable for use in Western Blot, Immunohistochemistry and ELISA. Other applications have not been tested. , Recommended Dilutions: Western Blot: 1:1000, Immunohistochemistry (FFPE): 1:10-1:50, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Keywords: Anti-NUMBL, Anti-Numb-R, Anti-Numb-like protein, Anti-Numb-related protein
Supplier: United States Biological
Supplier-Nr: 039212

Properties

Application: ELISA, IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human
Immunogen: NUMBL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 571-600 amino acids from the C-terminal region of human NUMBL.
Format: Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-NUMBL, CT (NUMBL, Numb-like protein, Numb-related protein)"
Write a review
or to review a product.
Viewed