Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AB-11454.20 20 µl - -

7 - 16 business days*

E-AB-11454.60 60 µl - -

7 - 16 business days*

E-AB-11454.120 120 µl - -

7 - 16 business days*

E-AB-11454.200 200 µl - -

7 - 16 business days*

The protein encoded by this gene plays a role in the determination of cell fates during... more
Product information "Anti-NUMB"
The protein encoded by this gene plays a role in the determination of cell fates during development. The encoded protein, whose degradation is induced in a proteasome-dependent manner by MDM2, is a membrane-bound protein that has been shown to associate with EPS15, LNX1, and NOTCH1. Four transcript variants encoding different isoforms have been found for this gene. Protein function: Plays a role in the process of neurogenesis. Required throughout embryonic neurogenesis to maintain neural progenitor cells, also called radial glial cells (RGCs), by allowing their daughter cells to choose progenitor over neuronal cell fate. Not required for the proliferation of neural progenitor cells before the onset of neurogenesis. Also involved postnatally in the subventricular zone (SVZ) neurogenesis by regulating SVZ neuroblasts survival and ependymal wall integrity. May also mediate local repair of brain ventricular wall damage. [The UniProt Consortium]
Keywords: Anti-h-Numb, Anti-Protein S171, Anti-Protein numb homolog, NUMB Polyclonal Antibody
Supplier: Elabscience
Supplier-Nr: E-AB-11454


Application: WB, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein of human NUMB
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Our products are for laboratory research use only: Not for administration to humans!
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