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Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
R1183-30H3.100 | 100 tests | - | - |
3 - 19 business days* |
796.00€
|
ROR-gamma is a 560aa novel DNA-binding transcription factor belonging to the ROR:RZR orphan... more
Product information "Anti-Nuclear Receptor ROR-gamma (Nuclear Receptor RZR-gamma, Nuclear Receptor Subfamily 1 Group F Me"
ROR-gamma is a 560aa novel DNA-binding transcription factor belonging to the ROR:RZR orphan nuclear receptor subfamily. The specific functions of this protein are not known. However, reports suggest that this protein is a ligand activated transcription factor and may be essential for lymphoid organogenesis (lymph nodes and Peyer's patches) and may play an important regulatory role in controlling apoptosis during thymopoiesis. ROR-gamma inhibits the expression of Fas ligand and IL2 and directs the differentiation program of proinflammatory IL-17+ T helper cells. ROR-gamma shares 50-51% sequence identity with RORA and RORB and is 88% identical to mouse ROR-gamma. It is highly expressed in skeletal muscle and at lower levels in various other tissues. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry (Intracellular): 10ul/10e6 cells (0.25ug), Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months at 4°C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light.
Keywords: | Anti-Nuclear receptor ROR-gamma, Anti-Nuclear receptor RZR-gamma, Anti-Retinoid-related orphan receptor-gamma, Anti-Nuclear receptor subfamily 1 group F member 3 |
Supplier: | United States Biological |
Supplier-Nr: | R1183-30H3 |
Properties
Application: | FC |
Antibody Type: | Monoclonal |
Clone: | 11E332 |
Conjugate: | Phycoerythrin |
Host: | Mouse |
Species reactivity: | human, mouse |
Immunogen: | Synthetic peptide corresponding to aa1-50 of human RORg. |
Format: | Affinity Purified |
Database Information
KEGG ID : | K08534 | Matching products |
UniProt ID : | P51449 | Matching products |
Gene ID | GeneID 6097 | Matching products |
Handling & Safety
Storage: | +4°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
Information about the product reference will follow.
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