Anti-Nuclear Receptor ROR-gamma (Nuclear Receptor RZR-gamma, Nuclear Receptor Subfamily 1 Group F Me

Anti-Nuclear Receptor ROR-gamma (Nuclear Receptor RZR-gamma, Nuclear Receptor Subfamily 1 Group F Me
Item number Size Datasheet Manual SDS Delivery time Quantity Price
R1183-30H3.100 100 tests - -

3 - 19 business days*

796.00€
 
ROR-gamma is a 560aa novel DNA-binding transcription factor belonging to the ROR:RZR orphan... more
Product information "Anti-Nuclear Receptor ROR-gamma (Nuclear Receptor RZR-gamma, Nuclear Receptor Subfamily 1 Group F Me"
ROR-gamma is a 560aa novel DNA-binding transcription factor belonging to the ROR:RZR orphan nuclear receptor subfamily. The specific functions of this protein are not known. However, reports suggest that this protein is a ligand activated transcription factor and may be essential for lymphoid organogenesis (lymph nodes and Peyer's patches) and may play an important regulatory role in controlling apoptosis during thymopoiesis. ROR-gamma inhibits the expression of Fas ligand and IL2 and directs the differentiation program of proinflammatory IL-17+ T helper cells. ROR-gamma shares 50-51% sequence identity with RORA and RORB and is 88% identical to mouse ROR-gamma. It is highly expressed in skeletal muscle and at lower levels in various other tissues. Applications: Suitable for use in Flow Cytometry. Other applications not tested. Recommended Dilution: Flow Cytometry (Intracellular): 10ul/10e6 cells (0.25ug), Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C before opening. DO NOT FREEZE! Stable at 4°C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months at 4°C. Freezing R-Phycoerythrin (PE) conjugates will result in a substantial loss of activity. PE conjugates are sensitive to light.
Keywords: Anti-Nuclear receptor ROR-gamma, Anti-Nuclear receptor RZR-gamma, Anti-Retinoid-related orphan receptor-gamma, Anti-Nuclear receptor subfamily 1 group F member 3
Supplier: United States Biological
Supplier-Nr: R1183-30H3

Properties

Application: FC
Antibody Type: Monoclonal
Clone: 11E332
Conjugate: Phycoerythrin
Host: Mouse
Species reactivity: human, mouse
Immunogen: Synthetic peptide corresponding to aa1-50 of human RORg.
Format: Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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