Anti-NOX4

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ARG55254.50 50 µg - -

6 - 14 business days*

439.00€
 
Protein function: Constitutive NADPH oxidase which generates superoxide intracellularly upon... more
Product information "Anti-NOX4"
Protein function: Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB. May produce superoxide in the nucleus and play a role in regulating gene expression upon cell stimulation. Isoform 3 is not functional. Isoform 5 and isoform 6 display reduced activity. [The UniProt Consortium]
Keywords: Anti-NOX4, Anti-KOX-1, Anti-RENOX, EC=1.6.3.-, Anti-NADPH oxidase 4, Anti-Kidney oxidase-1, Anti-Renal NAD(P)H-oxidase, Anti-Kidney superoxide-producing NADPH oxidase
Supplier: Arigo Biolaboratories
Supplier-Nr: ARG55254

Properties

Application: ELISA, IHC, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide around 14 aa (N-terminus) of Human NOX4 (Swiss: Q9NPH5)
MW: 64 kD
Format: Antigen Affinity Purified

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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