Anti-NOX4

Item number	Size	Datasheet	Manual	SDS	Delivery time	Quantity	Price
ARG55254.50	50 µg		-	-	6 - 14 business days*		520.00€

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Protein function: Constitutive NADPH oxidase which generates superoxide intracellularly upon... more

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Product information "Anti-NOX4"

Protein function: Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB. May produce superoxide in the nucleus and play a role in regulating gene expression upon cell stimulation. Isoform 3 is not functional. Isoform 5 and isoform 6 display reduced activity. [The UniProt Consortium]

Keywords:	Anti-NOX4, Anti-KOX-1, Anti-RENOX, EC=1.6.3.-, Anti-NADPH oxidase 4, Anti-Kidney oxidase-1, Anti-Renal NAD(P)H-oxidase, Anti-Kidney superoxide-producing NADPH oxidase
Supplier:	Arigo Biolaboratories
Supplier-Nr:	ARG55254

Properties

Application:	ELISA, IHC, WB
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Species reactivity:	human, mouse, rat
Immunogen:	Synthetic peptide around 14 aa (N-terminus) of Human NOX4 (Swiss: Q9NPH5)
MW:	64 kD
Format:	Antigen Affinity Purified