Anti-NOX4

Item number Size Datasheet Manual SDS Delivery time Quantity Price
600-401-DE1 100 µg - -

6 - 10 business days*

684.00€
 
Anti-NOX4 antibody was affinity purified from monospecific antiserum by immunoaffinity... more
Product information "Anti-NOX4"
Anti-NOX4 antibody was affinity purified from monospecific antiserum by immunoaffinity chromatography. NOX4 antibody is human, mouse, and rat reactive. At least four isoforms of NOX4 are known to exist. NOX4 is predicted to not cross-react with other NOX proteins. Protein function: Constitutive NADPH oxidase which generates superoxide intracellularly upon formation of a complex with CYBA/p22phox. Regulates signaling cascades probably through phosphatases inhibition. May function as an oxygen sensor regulating the KCNK3/TASK-1 potassium channel and HIF1A activity. May regulate insulin signaling cascade. May play a role in apoptosis, bone resorption and lipolysaccharide-mediated activation of NFKB. May produce superoxide in the nucleus and play a role in regulating gene expression upon cell stimulation. Isoform 3 is not functional. Isoform 5 and isoform 6 display reduced activity. [The UniProt Consortium]
Keywords: Anti-NOX4, Anti-RENOX, Anti-KOX-1, EC=1.6.3.-, Anti-NADPH oxidase 4, Anti-Kidney oxidase-1, Anti-Renal NAD(P)H-oxidase, Anti-Kidney superoxide-producing NADPH oxidase
Supplier: Rockland Immunochemicals
Supplier-Nr: 600-401-DE1

Properties

Application: ELISA, IHC, IFM, WB
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human, mouse, rat
Immunogen: 14 amino acid peptide near the N-terminus of human NOX4.
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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