Anti-NLRP3/NALP3, clone Cryo-2

Anti-NLRP3/NALP3, clone Cryo-2
Item number Size Datasheet Manual SDS Delivery time Quantity Price
AG-20B-0014-C100 100 µg -

approx. 1-3 business days

374.00€
 
Recognizes mouse and human NLRP3/NALP3. Liquid. In PBS containing 10% glycerol and 0.02% sodium... more
Product information "Anti-NLRP3/NALP3, clone Cryo-2"
Recognizes mouse and human NLRP3/NALP3. Liquid. In PBS containing 10% glycerol and 0.02% sodium azide. The inflammasome is a multiprotein complex that mediates the activation of caspase-1, which promotes, amongst others, the secretion of the proinflammatory cytokines interleukin (IL)-1beta and IL-18. Members of the Nod-like receptor family, including NLRP3/NALP3, are critical components of the inflammasome that link danger-signals to caspase-1 activation. Defects in NLRP3 are the cause of familial cold autoinflammatory syndrome type 1 (FCAS1), Muckle-Wells syndrome (MWS) and of chronic infantile neurologic cutaneous and articular syndrome (CINCA).
Keywords: NACHT-, LRR- and PYD-containing Protein 3, NLRP3, Cryopyrin, Cold Autoinflammatory Syndrome 1 Protein
Supplier: AdipoGen Life Sciences
Supplier-Nr: AG-20B-0014

Properties

Application: IHC, IP, WB, ICC, ChIP
Antibody Type: Monoclonal
Clone: Cryo-2
Conjugate: No
Host: Mouse
Species reactivity: human , mouse
Immunogen: Recombinant mouse NLRP3/NALP3 (pyrin domain/aa 1-93).
Format: Purified

Database Information

KEGG ID : K12800 | Matching products
UniProt ID : Q8R4B8 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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