Anti-NLRC4

Item number Size Datasheet Manual SDS Delivery time Quantity Price
E-AB-52183.20 20 µl -

7 - 16 business days*

71.00€
E-AB-52183.60 60 µl -

7 - 16 business days*

143.00€
E-AB-52183.120 120 µl -

7 - 16 business days*

238.00€
E-AB-52183.200 200 µl -

7 - 16 business days*

396.00€
 
This gene encodes a member of the caspase recruitment domain-containing NLR family. Family... more
Product information "Anti-NLRC4"
This gene encodes a member of the caspase recruitment domain-containing NLR family. Family members play essential roles in innate immune response to a wide range of pathogenic organisms, tissue damage and other cellular stresses. Mutations in this gene result in autoinflammation with infantile enterocolitis. Alternative splicing results in multiple transcript variants. Protein function: Key component of inflammasomes that indirectly senses specific proteins from pathogenic bacteria and fungi and responds by assembling an inflammasome complex that promotes caspase-1 activation, cytokine production and macrophage pyroptosis (PubMed:15107016). The NLRC4 inflammasome is activated as part of the innate immune response to a range of intracellular bacteria. [The UniProt Consortium]
Keywords: Anti-Ipaf, Anti-NLRC4, Anti-CARD12, Anti-Clan protein, Anti-Ice protease-activating factor, Anti-CARD, LRR, and NACHT-containing protein, Anti-NLR family CARD domain-containing protein 4, Anti-Caspase recruitment domain-containing protein 12, NLRC4 Polycl
Supplier: Elabscience
Supplier-Nr: E-AB-52183

Properties

Application: IHC, ELISA
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Species reactivity: human
Immunogen: Fusion protein of human NLRC4

Handling & Safety

Storage: -20°C
Shipping: 4°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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