Anti-NKX2.2 (Neuroendocrine & Ewing's Sarcoma Marker) (clone: rNX2/294) (recombinant monoclonal)

Item number Size Datasheet Manual SDS Delivery time Quantity Price
ABE-12-1009-20 20 µg -

3 - 11 business days*

373.00€
 
Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential... more
Product information "Anti-NKX2.2 (Neuroendocrine & Ewing's Sarcoma Marker) (clone: rNX2/294) (recombinant monoclonal)"
Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors. Protein function: Transcriptional activator involved in the development of insulin-producting beta cells in the endocrine pancreas. May also be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Binds to elements within the NEUROD1 promoter. [The UniProt Consortium]
Keywords: Anti-NKX2-2, Anti-NKX2.2, Anti-Homeobox protein Nkx-2.2, Anti-Homeobox protein NK-2 homolog B, Recombinant Mouse Monoclonal Antibody to NKX2.2 (Neuroendocrine & Ewing's Sarcoma Marker)(Clone : rNX2/294)
Supplier: Abeomics
Supplier-Nr: 12-1009-20

Properties

Application: FC, IF, IHC
Antibody Type: Monoclonal
Clone: rNX2/294
Conjugate: No
Host: Mouse
Species reactivity: human, mouse, rat, chicken
Immunogen: Human full-length recombinant NKX2.2 protein
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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