Anti-NKX2.2 (Homeobox protein NKX)

Anti-NKX2.2 (Homeobox protein NKX)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
138578-AF.100 100 µg - -

3 - 19 business days*

659.00€
 
Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential... more
Product information "Anti-NKX2.2 (Homeobox protein NKX)"
Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors. Applications: Suitable for use in Western Blot, Flow Cytometry, Immunofluorescence, Immunoprecipitation and Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (FFPE): Requires HIER using sodium citrate buffer pH6.0 prior to staining., Optimal dilutions to be determined by the researcher. Positive Control: Pancreas or Ewing sarcoma, Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Supplier: United States Biological
Supplier-Nr: 138578-AF

Properties

Application: ELISA, FC, IF, IHC, IP, WB
Antibody Type: Monoclonal
Clone: NX2/294
Conjugate: No
Host: Mouse
Species reactivity: human
Format: Affinity Purified

Database Information

UniProt ID : O95096 | Matching products

Handling & Safety

Storage: -20°C
Shipping: +4°C (International: °C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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