Anti-NKX2.2, clone NX2/1524

Anti-NKX2.2, clone NX2/1524
Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-V3362-20UG 20 µg - -

3 - 10 business days

251.00€
NSJ-V3362-100UG 100 µg - -

3 - 10 business days

541.00€
 
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. Expression of NKX2.2... more
Product information "Anti-NKX2.2, clone NX2/1524"
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide. Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. It acts as a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors. Protein function: Acts as a transcriptional activator. Required for the maintenance of NEUROD1 expression in the horomone-producing endocrine cells of the pancreas. May be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Associates with chromatin at the NEUROD1 promoter region. Binds to a subset of consensus elements within the NEUROD1 promoter. [The UniProt Consortium]
Keywords: Anti-NKX2-2, Anti-NKX2.2, Anti-Homeobox protein Nkx-2.2, Anti-Homeobox protein NK-2 homolog B, NKX2.2 Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: V3362-20UG

Properties

Application: FC, IHC (paraffin), IF
Antibody Type: Monoclonal
Clone: NX2/1524
Conjugate: No
Host: Mouse
Reactivity: Human
Immunogen: A human partial recombinant protein corresponding to amino acids 1-119 was used as the immunogen for this NKX2.2 antibody.
Format: Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
You will get a certificate here
or to request a certificate of analysis.
Read, write and discuss reviews... more
Customer review for "Anti-NKX2.2, clone NX2/1524"
Write a review
or to review a product.
Viewed