Anti-NFKBIB, CT (NFKBIB, IKBB, TRIP9, NF-kappa-B inhibitor beta, I-kappa-B-beta, Thyroid receptor-in

Anti-NFKBIB, CT (NFKBIB, IKBB, TRIP9, NF-kappa-B inhibitor beta, I-kappa-B-beta, Thyroid receptor-in
Item number Size Datasheet Manual SDS Delivery time Quantity Price
038941-APC.200 200 µl - -

3 - 19 business days*

993.00€
 
NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA (MIM 164014), or RELB... more
Product information "Anti-NFKBIB, CT (NFKBIB, IKBB, TRIP9, NF-kappa-B inhibitor beta, I-kappa-B-beta, Thyroid receptor-in"
NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA (MIM 164014), or RELB (MIM 604758) to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008, or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664 or IKBKB, MIM 603258) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T, R is an A or G purine, and Y is a C or T pyrimidine). Applications: Suitable for use in Western Blot, Immunohistochemistry, FLISA, Recommended Dilution: FLISA: 1:1,000, Western Blot: 1:100-500, Immunohistochemistry: 1:10-50, Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap., , Note: Applications are based on unconjugated antibody.
Keywords: Anti-IKBB, Anti-IkB-B, Anti-NFKBIB, Anti-TRIP-9, Anti-IkB-beta, Anti-IkappaBbeta, Anti-NF-kappa-BIB, Anti-I-kappa-B-beta, Anti-TR-interacting protein 9, Anti-NF-kappa-B inhibitor beta, Anti-Thyroid receptor-interacting protein 9
Supplier: United States Biological
Supplier-Nr: 038941-APC

Properties

Application: FLISA, IHC, WB
Antibody Type: Polyclonal
Conjugate: APC
Host: Rabbit
Species reactivity: human
Immunogen: NFKBIB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 325-355 amino acids from the C-terminal region of human NFKBIB.
Format: Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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