Anti-NFKB, p105, CT (S933) (NFKB1, Nuclear factor NF-kappa-B p105 subunit, DNA-binding factor KBF1,

Anti-NFKB, p105, CT (S933) (NFKB1, Nuclear factor NF-kappa-B p105 subunit, DNA-binding factor KBF1,
Item number Size Datasheet Manual SDS Delivery time Quantity Price
038937-APC.200 200 µl - -

3 - 19 business days*

993.00€
 
This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S... more
Product information "Anti-NFKB, p105, CT (S933) (NFKB1, Nuclear factor NF-kappa-B p105 subunit, DNA-binding factor KBF1,"
This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene. Applications: Suitable for use in Western Blot, FLISA, Recommended Dilution: FLISA: 1:1,000, Western Blot: 1:100-500, Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap., , Note: Applications are based on unconjugated antibody.
Keywords: Anti-NFKB1
Supplier: United States Biological
Supplier-Nr: 038937-APC

Properties

Application: FLISA, WB
Antibody Type: Polyclonal
Conjugate: APC
Host: Rabbit
Species reactivity: human
Immunogen: NFKB(p105) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 912-938 amino acids from the C-terminal region of human NFKB(p105).
Format: Affinity Purified

Handling & Safety

Storage: +4°C
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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