Anti-Neuropeptide Y (NPY, Neuropeptide Tyrosine, Neuropeptide Y Precursor, PYY4, Y Neuropeptide)

Anti-Neuropeptide Y (NPY, Neuropeptide Tyrosine, Neuropeptide Y Precursor, PYY4, Y Neuropeptide)
Item number Size Datasheet Manual SDS Delivery time Quantity Price
N2176-60B.50 50 µl - -

3 - 19 business days

447.00€
 
Neuropeptide Y (NPY), a 36 amino acid peptide amide, is a major regulatory neuropeptide widely... more
Product information "Anti-Neuropeptide Y (NPY, Neuropeptide Tyrosine, Neuropeptide Y Precursor, PYY4, Y Neuropeptide)"
Neuropeptide Y (NPY), a 36 amino acid peptide amide, is a major regulatory neuropeptide widely distributed in the mammalian central (CNS) and peripheral nervous systems (PNS). NPY belongs to the pancreatic polypeptide family of peptides which are characterized by a common tertiary structure (1,2). Within this family, an intestinal peptide hormone, peptide YY (PYY), is most closely related to NPY. In the CNS, NPY is involved in regulation of blood pressure, memory processing, circadian rhythm, and stimulation of food intake (2). In the PNS, NPY has potent vasoconstrictor activity and acts as a neurotransmitter/neuromodulator of sympathetic neurons and adrenal glands (3,4). NPY is one of the most abundant peptides found in the CNS, widely distributed in the brain. High levels of NPY are present in the cerebral cortex, amygdaloid nuclei, hippocampal formation, and hypothalamus (5-7). In the PNS, NPY is found mainly in sympathetic neurons that innervate vascular smooth muscle, heart, and urogenital tract (3,8,9) The biological actions of NPY in the brain and periphery are mediated by at least two different NPY receptors, designated Y1 and Y2 receptor subtypes (10-11). Applications: Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. Recommended Dilutions: Indirect ELISA: 1:5000-1:10,000 using peptide coating at 0.5-1ug/well in 0.05M carbonate/bicarbonate buffer, pH 9.6 and pNPP as substrate, Immunohistochemistry (Frozen): 1:8000-1:16,000 using 4% paraformaldehyde perfusion-fixed sections of rat brain, Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Supplier: United States Biological
Supplier-Nr: N2176-60B

Properties

Application: ELISA, IHC
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Swine, Rat, Sheep (Expected: Bovine, Cat, Human, Monkey, Mouse, Swine, Rabbit, Rat)
Immunogen: Synthetic Neuropeptide Y (porcine) conjugated to KLH.
Purity: Whole antisera
Format: Serum

Database Information

Handling & Safety

Storage: -20°C (-20°C Glycerol)
Shipping: +4°C (International: +4°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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