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Anti-Nestin

Item number Size Datasheet Manual SDS Delivery time Quantity Price
NSJ-R32111 100 µg - -

3 - 10 business days

503.00€
 
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Nestin is a type VI intermediate filament... more
Product information "Anti-Nestin"
0.5mg/ml if reconstituted with 0.2ml sterile DI water. Nestin is a type VI intermediate filament (IF) protein that in humans is encoded by the NES gene. Distribution and expression of nestin in mitotically active cells suggests it plays a role in regulation of the assembly and disassembly of intermediate filaments, which, together with other structural proteins, participate in remodeling of the cell. The role of nestin in dynamic cells, particularly structural organization of the cell, appears strictly regulated by phosphorylation, especially its integration into heterogeneous intermediate filaments together with vimentin or alpha-internexin. Furthermore, nestin expression has been extensively used as a marker for central nervous system (CNS) progenitor cells in different contexts, based on observations indicating a correlation between nestin expression and this cell type in vivo. Protein function: Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells. [The UniProt Consortium]
Keywords: Anti-NES, Anti-Nestin, Anti-Nbla00170, Nestin Antibody
Supplier: NSJ Bioreagents
Supplier-Nr: R32111

Properties

Application: WB, IHC (paraffin), IHC (frozen)
Antibody Type: Polyclonal
Conjugate: No
Host: Rabbit
Reactivity: Human, Rat
Immunogen: Amino acids ERLRATEKFQLAVEALEQEKQGLQSQIAQVLEGRQQLAH of human NES were used as the immunogen for the Nestin antibody.
Format: Purified

Handling & Safety

Storage: -20°C
Shipping: -20°C (International: -20°C)
Caution
Our products are for laboratory research use only: Not for administration to humans!
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