
Item number | Size | Datasheet | Manual | SDS | Delivery time | Quantity | Price |
---|---|---|---|---|---|---|---|
NSJ-F53752-0.4ML | 400 µl | - | - | 3 - 10 business days | 503.00€ |
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In 1X PBS, pH 7.4, with 0.09% sodium azide. Nestin is a class VI intermediate filament protein... more
Product information "Anti-Nestin"
In 1X PBS, pH 7.4, with 0.09% sodium azide. Nestin is a class VI intermediate filament protein expressed predominantly in stem cells of the neural tube but absent from virtually all differentiated CNS cells. In the CNS, nestin is downregulated upon differentiation and replaced by neurofilaments. Transient expression of nestin has been postulated as a key step committing cells to the neural differentiation pathway. Nestin expression has also been observed in pancreatic hematopoietic stem cell populations. Protein function: Required for brain and eye development. Promotes the disassembly of phosphorylated vimentin intermediate filaments (IF) during mitosis and may play a role in the trafficking and distribution of IF proteins and other cellular factors to daughter cells during progenitor cell division. Required for survival, renewal and mitogen-stimulated proliferation of neural progenitor cells. [The UniProt Consortium]
Keywords: | Anti-NES, Anti-Nestin, Anti-Nbla00170, Nestin Antibody |
Supplier: | NSJ Bioreagents |
Supplier-Nr: | F53752-0.4ML |
Properties
Application: | IHC, IF, ELISA |
Antibody Type: | Polyclonal |
Conjugate: | No |
Host: | Rabbit |
Reactivity: | Human, Mouse |
Immunogen: | A portion of amino acids 1560-1590 from the human protein was used as the immunogen for this Nestin antibody. |
Format: | Purified |
Database Information
KEGG ID : | K07609 | Search using KEGG ID |
UniProt ID : | P48681 | Search using UniProt ID |
Gene ID | GeneID 10763 | Search using Gene ID |
Handling & Safety
Storage: | -20°C |
Shipping: | +4°C (International: +4°C) |
Caution
Our products are for laboratory research use only: Not for administration to humans!
Our products are for laboratory research use only: Not for administration to humans!
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