Anti-NELFA

Item number	Size	Manual	Delivery time	Price
A301-910A-T	20 µl (2 blots)	-	3 - 9 business days*	131.00€
A301-910A-M	100 µl (10 blots)	-	3 - 9 business days*	313.00€
A301-910A	100 µl (100 µg)	-	3 - 9 business days*	465.00€

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Protein function: Essential component of the NELF complex, a complex that negatively regulates... more

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Product information "Anti-NELFA"

Protein function: Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which acts via an association with the DSIF complex and causes transcriptional pausing, is counteracted by the P-TEFb kinase complex. The NELF complex is involved in HIV-1 latency possibly involving recruitment of PCF11 to paused RNA polymerase II. In vitro, the NELFA:NELFCD subcomplex binds to ssDNA and ssRNA in a sequence- and structure-dependent manner. Probably required to interact with the RNA polymerase II complex. [The UniProt Consortium]

Keywords:	Anti-NELFA, Anti-WHSC2, Anti-NELF-A, Anti-Negative elongation factor A, Anti-Wolf-Hirschhorn syndrome candidate 2 protein
Supplier:	Bethyl Laboratories
Supplier-Nr:	A301-910A

Properties

Application:	WB, IP, IHC
Antibody Type:	Polyclonal
Conjugate:	No
Host:	Rabbit
Reactivity:	Human (Expected: Mouse)
Immunogen:	synthetic peptide. The epitope recognized by A301-910A-T maps to a region between residue 499 and 549 of human negative elongation factor A using the numbering given in entry BAB18651.1 (GeneID 7469).
Format:	Antigen Affinity Purified